Myouclear Breakdown in Sporadic Inclusion Body Myositis
نویسندگان
چکیده
منابع مشابه
Inclusion body myositis: current pathogenetic concepts and diagnostic and therapeutic approaches.
Inclusion body myositis is the most common acquired muscle disease in older individuals, and its prevalence varies among countries and ethnic groups. The aetiology and pathogenesis of sporadic inclusion body myositis are still poorly understood; however genetic factors, ageing, and environmental triggers might all have a role. Unlike other inflammatory myopathies, sporadic inclusion body myosit...
متن کاملMisdiagnosis of inclusion body myositis: two case reports and a retrospective chart review
INTRODUCTION Sporadic inclusion body myositis is the most common adult myopathy in persons aged 50 years and older. The clinical presentation includes a chronic, slowly progressive course with a predilection for weakness of the forearm flexors and quadriceps muscles. Its indolent course makes it a disease frequently missed or misdiagnosed as other neuromuscular conditions by health care profess...
متن کاملInclusion-body myositis, a multifactorial muscle disease associated with aging: current concepts of pathogenesis.
PURPOSE OF REVIEW Sporadic inclusion-body myositis, the most common muscle disease of older persons, has no known cause or persistently beneficial treatment. The unfolding pathogenesis could lead to new treatment strategies and it is now of growing interest among clinicians and basic scientists. About 100 papers related to the subject were published in 2006 and the first part of 2007 (we cite o...
متن کاملDiagnosis and classification of sporadic inclusion body myositis (sIBM).
Sporadic inclusion body myositis (sIBM) is the most common acquired muscle disease in elderly individuals, particularly men. Its prevalence varies among ethnic groups but is estimated at 35 per one million people over 50. Genetic as well as environmental factors and autoimmune processes might both have a role in its pathogenesis. Unlike other inflammatory myopathies, sIBM causes very slowly pro...
متن کاملLong-term observational study of sporadic inclusion body myositis.
We describe a long-term observational study of a large cohort of patients with sporadic inclusion body myositis and propose a sporadic inclusion body myositis weakness composite index that is easy to perform during a clinic. Data collection from two groups of patients (Paris and Oxford) was completed either during a clinic visit (52%), or by extraction from previous medical records (48%). One h...
متن کامل